40 years
of fighting

Our vision is to end NF

The Children's Tumor Foundation's mission is to drive research, expand knowledge, and advance care for the NF community.


Research for a cure

Since its formation, the Children’s Tumor Foundation has been crucial to the development of solid scientific data about the genetic disorder neurofibromatosis (NF). Thanks to the generosity of our donors and supporters, we are breaking through barriers and forging the pathway that will lead to a cure.

Get to know our NF Heroes

Latest News


Selumetinib Granted Orphan Drug Designation by the FDA for NF1

Feb 15, 2018, Posted in Latest News, NF1, Science

AstraZeneca and Merck today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) for selumetinib, a MEK 1/2 inhibitor, for the treatment of neurofibromatosis type 1 (NF1). Selumetinib was shown to be effective in shrinking tumors because of an early-stage investment of the Children Tumor Foundation. Over 70% of participants in this MEK clinical trial are showing reductions in tumor size from 20-50% of their inoperable plexiform neurofibromas.

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Registration for the 2018 NF Conference is now open

Feb 14, 2018, Posted in Latest News, NF Conference, Science

Join us November 2-6, 2018 in Paris, France for the Joint Global Neurofibromoatosis Conference, a global event attracting more than 800 participants worldwide across a wide range of scientific disciplines, from research and clinical backgrounds, all focused on improving outcomes for patients with neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis.

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Young Investigator recipient Lai Man (Natalie) Wu Authors Study about MPNSTs Published in Cancer Cell

Feb 14, 2018, Posted in Awards, CTF in the News, Latest News, NF1, Published, Science

Lai Man (Natalie) Wu, PhD, of Cincinnati Children’s Hospital Medical Center, is first author on a recently published article in Cancer Cell. This study, funded in part by a 2017 Young Investigator Award from the Children’s Tumor Foundation, suggests ways to attack MPNSTs.

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Stories of NF: Zeynep G.

Feb 7, 2018, Posted in NF Hero, NF1

I was diagnosed with NF1 when I was about 6 or 7 years old. I have 3-4 plexiform neurofibromas. I have healed scoliosis (I had surgery as a child). I am a lawyer and I live in Turkey.

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